Table 5.
Univariate survival analysis for disease-free and overall survival in all patients.
| Variables | Disease-free survival | Overall survival | ||||
|---|---|---|---|---|---|---|
| Hazard ratio (95% C.I.) | P value | Events | Hazard ratio (95% C.I.) | P value | Events | |
| Age | 0.91 (0.45–1.84) | 0.8 | 9 (47.4) | 1.07 (0.47–2.43) | 0.87 | 7 (36.8) |
| Gender | 0.73 (0.35–1.51) | 0.4 | 10 (43.5) | 0.94 (0.43–2.05) | 0.87 | 9 (39.1) |
| Tobacco chewing | 2.29 (1.2–4.34) | 0.01 | 35 (61.4) | 2.45 (1.16–5.21) | 0.02 | 30 (53.6) |
| Tobacco smoking | 1.39 (0.77–2.5) | 0.28 | 19 (63.3) | 1.74 (0.91–3.35) | 0.09 | 17(56.7) |
| Alcohol | 1.85 (1.04–3.29) | 0.04 | 24 (61.5) | 2.36 (1.23–4.55) | 0.01 | 22 (57.9) |
| Habits | 1.46 (1–2.13) | 0.05 | 22 (55) | 1.78 (1.12–2.84) | 0.01 | 24 (58.5) |
| Node status | 2.6 (1.39–4.88) | 0.003 | 35 (67.3) | 2.67 (1.29–5.52) | 0.008 | 29 (58) |
| Stage | 2.16 (1.18–3.96) | 0.01 | 34 (66.7) | 2.45 (1.21–4.96) | 0.01 | 29 (59.2) |
| Grade | 1.18 (0.77–1.82) | 0.45 | 10 (66.7) | 1.68 (1.02–2.78) | 0.04 | 10 (66.7) |
| PNI | 0.99 (0.44–2.22) | 0.99 | 7 (46.7) | 0.85 (0.33–2.17) | 0.73 | 5 (38.5) |
| Occult node status | 4.27 (1.53–11.91) | 0.005 | 8 (53.3) | 5.19 (1.46–18.46) | 0.01 | 6 (46.2) |
| LAMC2 | 2.69 (1.38–5.22) | 0.004 | 33 (66) | 2.91 (1.36–6.21) | 0.006 | 27 (54) |
| ECAD at ITF | 3.19 (1.64–6.23) | 0.001 | 31 (75.6) | 3.11 (1.48–6.51) | 0.003 | 24 (58.5) |
| MMP9 | 5.39 (1.88–15.48) | 0.002 | 31 (83.8) | 3.09 (1.07–8.9) | 0.04 | 25 (67.6) |
Factors denoting increased hazard of death and recurrence in OTSCC; Numbers in brackets denote percentages. The numbers in bold denote values that are of statistical significance.