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. 2021 Jan 8;11:258. doi: 10.1038/s41598-020-79437-1

Table 2.

Optical coherence tomography findings of the 5 mg/mL MNU group (n = 10) and 10 mg/mL MNU groups (n = 13).

Baseline Week 2 Week 6 (12)a p-value between baseline and Week 2 p-value between Week 2 and Week 6 (12)a p-value between baseline and Week 6 (12)a
Mean INL thickness in 5 mg/mL MNU group (μm) 22.38 ± 4.93 17.46 ± 7.58 19.41 ± 3.89 < 0.001b 0.831b < 0.001b
Mean ONL thickness in 5 mg/mL MNU group (μm) 32.93 ± 9.56 13.92 ± 7.31 14.44 ± 5.69 < 0.001b 0.575b < 0.001b
Mean TR thickness in 5 mg/mL MNU group (μm) 201.10 ± 24.95 151.20 ± 38.11 156.74 ± 15.01 < 0.001b 0.136b < 0.001b
Mean INL thickness in 10 mg/mL MNU group (μm) 21.80 ± 5.81 12.80 ± 2.78 12.34 ± 3.40 < 0.001b 0.831b < 0.001b
Mean ONL thickness (μm) in 10 mg/mL MNU group (μm) 37.93 ± 6.13 16.20 ± 8.35 12.15 ± 8.97 < 0.001b 0.575b < 0.001b
Mean TR thickness in 10 mg/mL MNU group (μm) 201.10 ± 24.95 144.00 ± 34.88 136.77 ± 43.39 < 0.001b 0.136b < 0.001b

INL inner nuclear layer, MNU N-methyl-N-nitrosourea, ONL outer nuclear layer, POD postoperative day, TR total retinal thickness.

aAt week 12 in 10 mg/mL MNU group.

bWilcoxon-signed ranked test.