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. 2021 Jan 9;30(2):440–448. doi: 10.1007/s00044-020-02679-1

Table 1.

HCMV replication assay p97 inhibitors

Compounds EC50 (μM) ± s.d.a CC50 (μM) ± s.d.a TIb
NMS-873 2.2 ± 2.5 4.1 ± 3.3 1.9
CB-5083 0.72 ± 1.1 0.53 ± 0.1 0.7
LC-0912 2.1 ± 2.5 3.3 ± 2.3 1.6
LC-1309 0.6 ± 0.2 2 ± 0 3.3
LC-1310 0.3 ± 0 12 ± 10 40

as.d. standard deviation

bTissue culture therapeutic index (CC50/EC50)