Figure 1. Taste Reactivity Test.
Rats (n=8) were subjected to this test across two days. On the first day they were treated with vehicle (Veh) and the second day with 2.4μg/kg Exendin-4 (Ex-4). A. Mean number of appetitive bouts/15 min intraoral (IO) delivery of 0.5 M sucrose in rats treated with Veh or Ex-4.B. Mean number of tongue protrusions (TP) or lateral tongue protrusions (LTP) during the 15 min IO delivery of 0.5 M sucrose in rats treated with Veh or Ex-4.C. Mean time (seconds) of paw-licking (PL) during the 15 min IO delivery of 0.5 M sucrose in rats treated with Veh or Ex-4. D. Mean number of passive drips emitted during the 15 min IO delivery of 0.5 M sucrose for Veh and Ex-4 treated rats. E. Mean log 10 latency (in sec) to elicit the 1st gape to sucrose for Veh and Ex-4 treated rats F. Mean number of aversive responses (gapes) elicited by intraoral infusion of 0.5 M sucrose in Veh vs. Ex-4 treated rats. *p<0.005