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Pathway analysis of downregulated genes in the liver of HFD mice. (A) Downregulated NR signaling pathways and genes associated brown adipose tissue based on ChEA and Mouse Gene Atlas database; (B) A cluster graph of gene expression profiles of downregulated NR signaling according to ChEA database; (C) GSEA profiles of PPAR signaling in HFD with and without luteolin treatment.
