5-FU	Fluorouracil
ACVR2	Activin receptor type 2
AFAP	Attenuated familial adenomatous polyposis
ALP	Alpelisib
AMPK	Adenosine monophosphate-activated protein kinase
APC	Adenomatous polyposis coli
BRAF	Serine/threonine-protein kinase B-Raf
Bub	Budding uninhibited by benzimidazoles
CDC20	Cell division cycle 20
CDKN	Cyclin-dependent kinases
CIMP	CpG island methylator phenotype
CIN	Chromosomal instability
CMS	Consensus molecular subtypes
COX	Cyclooxygenase
CRC	Colorectal cancer
CTNNB1	Catenin beta-1
DCC	Deleted in colorectal cancer
dMMR	Defective mismatch repair
EDM	Exonuclease domain
EGFR	Epidermal growth factor receptor
ERK	Extracellular signal related kinase
FAP	Familial adenomatous polyposis
FDA	Food and Drug Administration
FOLFOX	Folinic acid, fluorouracil, and oxaliplatin
GSH	Glutathione
GSK3-β	Glycogen synthase kinase 3-β
HNPCC	Hereditary non-polyposis colorectal cancer
IBD	Inflammatory bowel disease; Ig: Immunoglobin
IGFBP7	Insulin-like growth factor-binding protein 7
JAK	Janus kinase
KRAS	Kirsten ras
LOH	Loss of heterozygosity
LV	Leucovorin
MAP	MUTYH-associated polyposis
MAP/MEK	Mitogen-activated protein kinase
MLH/MSH	MutL homolog
MSI	Microsatellite instability
MSS	Microsatellite stable
NF-κB	Nuclear factor kappa
NSAIDs	Non-steroidal anti-inflammatory drugs
OS	Overall survival
PD-1/PD-L1	Programmed death ligand-1
PI3K	Phosphatidylinositol 3-kinase
PI3KCA	Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Alpha
POLE/POLD1	Polymerase epsilon or delta 1
RAC1	Rac family small GTPase 1
ROS	Reactive oxygen species
SCNAs	Somatic copy number alterations
SMAD	Small mothers against decapentaplegic
STAT	Signal transducer and activator of transcription
TCGA	The Cancer Genome Atlas
TGF-β	Transforming growth factor-β
TIGAR	T53-induced glycolysis regulatory phosphatase
TNM	Tumor-nodes-metastasis
TP53	Tumor protein 53
TSG	Tumor suppressor gene
VEGF	Vascular endothelial growth factor
VEGFR	Vascular endothelial growth factor receptor
Wnt	Wingless