Table 4.
Exclusions of data from clinical studies post-acquisition.
Author | All Data included? | Size of Study | What Was Excluded? | Why? |
---|---|---|---|---|
Carter (1998) [35] | No | 4 patients 5 treatments |
Not stated | Artefacts |
Craciunescu (2001) [33] | Yes | 2 patients | - | - |
Craciunescu (2009) [31] | No | 10 patients 40 treatments |
4 patients 12 treatments |
Lack of MR information in HT treatments performed outside the MR scanner, image/motion artefacts, uncorrectable drift, impossibility to localize the fiber optic probes, missing/corrupted data files |
Dadakova (2015) [32] | No | 3 patients 20 treatments |
1 patient 1 treatment |
Susceptibility artefact in the ROI from air in rectum |
Gellermann (2005) [36] | No | 15 patients | Everything but 1 best session per patient | MR data sets incomplete and/or disturbed by technical reasons |
Gellermann (2006) [21] | No | 9 patients 30 treatments |
15 treatments | Breakdown or malfunction of applicator, restlessness of the patient |
Peller (2002) [28] | No | 1 patient | “Data sets” | Artefacts |
Stauffer (2009) [30] | No | 10 patients | 3 patients All except 12 treatments |
Uncorrected field drift or inability to locate or correlate sensor positions or significant patient position shift early in treatment |
Unsoeld (2020) [17] | No | 24 patients | 13 patients: 11 patients with abdominal and pelvic tumors; 1 patient with different time course of therapy; 1 patient without surgery | Breathing and intestinal motion artefacts in MRT data; pathological response is not comparable; lack of information on pathological response |
Wu (2020) [34] | No | 4 patients | 2 patients | Bulk motion due to discomfort during treatment, ROI contained too much gas |