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. 2020 Dec 24;13(1):31. doi: 10.3390/cancers13010031

Table 4.

Exclusions of data from clinical studies post-acquisition.

Author All Data included? Size of Study What Was Excluded? Why?
Carter (1998) [35] No 4 patients
5 treatments
Not stated Artefacts
Craciunescu (2001) [33] Yes 2 patients - -
Craciunescu (2009) [31] No 10 patients
40 treatments
4 patients
12 treatments
Lack of MR information in HT treatments
performed outside the MR scanner, image/motion artefacts, uncorrectable drift, impossibility to localize the fiber optic probes, missing/corrupted data files
Dadakova (2015) [32] No 3 patients
20 treatments
1 patient
1 treatment
Susceptibility artefact in the ROI from air in rectum
Gellermann (2005) [36] No 15 patients Everything but 1 best session per patient MR data sets incomplete and/or disturbed by technical reasons
Gellermann (2006) [21] No 9 patients
30 treatments
15 treatments Breakdown or malfunction of applicator, restlessness of the patient
Peller (2002) [28] No 1 patient “Data sets” Artefacts
Stauffer (2009) [30] No 10 patients 3 patients
All except 12 treatments
Uncorrected field drift or inability to locate or correlate sensor positions or significant patient position shift early in treatment
Unsoeld (2020) [17] No 24 patients 13 patients: 11 patients with abdominal and pelvic tumors; 1 patient with different time course of therapy; 1 patient without surgery Breathing and intestinal motion artefacts in MRT data; pathological response is not comparable; lack of information on pathological response
Wu (2020) [34] No 4 patients 2 patients Bulk motion due to discomfort during treatment, ROI contained too much gas