Table 5.
Pre-clinical studies by the year of publication; including technique/method investigated, improvement found (where applicable) and main aim of the study. Feasibility and comparison studies are presented in grey. Studies satisfying our performance criterion are highlighted in green.
| Author | Year | Technique/Method Investigated | Improvement | Main Aim |
|---|---|---|---|---|
| Wu [34] | 2020 | Correction of motion-induced susceptibility artifacts | TNR improvement | B0 changes and image gaps due to motion, B0 drift |
| Ferrer [37] | 2020 | Different B0 drift corrections | IQR improved from 9.31 to 0.80 °C. ME improved from −4.30 to 0.33 °C | B0 drift |
| Bing [38] | 2019 | Forced breath-hold MR-HIFU | Accuracy and stability from 1.2 to 0.6 °C and from 1.4 to 0.8 °C | B0 changes and image gaps due to motion |
| Odeen [39] | 2019 | Different protocols for PRFS MRT for LITT | Factor 2 improvement in the temperature SD | Comparison |
| Tan [40] | 2019 | Motion compensation using principal component analysis and projection onto dipole fields | Reduces temperature SD from 3.02 to 0.86 °C | B0 changes and image gaps due to motion |
| Wu [41] | 2019 | Novel fast spin echo method | TNR efficiency improved by 25% | Feasibility |
| Zhu [42] | 2019 | Feasibility/safety of MRgHIFU | N/A | Feasibility |
| Jonathan [43] | 2018 | Proposed and validated a hybrid radial-EPI temperature mapping pulse sequence | Provides whole brain coverage, temperature SD was 48% higher than standard | Feasibility |
| Kothapalli [44] | 2018 | MRT performance at different anatomical sites | N/A | Comparison |
| Chu [45] | 2016 | Feasibility (safety + performance) MRgHIFU for rectal cancer | Precision and stability of temperature improved from 7.8 and 2.3 °C to 0.3 and 0.6 °C | Feasibility |
| Svedin [46] | 2016 | Correction of respiration artifact in 3D MRT using phase navigators | Temperature measurement improved by a factor of 2.1 | B0 changes and image gaps due to motion |
| Tillander [47] | 2016 | Hyperthermia for deep-seated heating volumes using HIFU | N/A | Feasibility |
| Boulant [48] | 2015 | FID navigator to correct for B0 field and variations induced by breathing | Reduces the temperature SD of the data over the first 8 min from 0.2 to 0.05 °C | B0 drift and B0 changes due to motion |
| De Senneville [49] | 2015 | Approach for motion estimation of abdominal organs | Temperature SD improvement of 0.4 °C and reduction of artefacts by up to 3 °C | B0 changes and image gaps due to motion |
| Gaur [50] | 2015 | Reconstruction method to accelerate MRT | Achieves same temperature error at up to 32× acceleration factors | Acceleration |
| Marx [51] | 2015 | MASTER sequence | Temperature SD improvement from 1.21 to 0.82 °C | Feasibility |
| Mei [52] | 2015 | Different methods for B0 inhomogeneity correction | None | B0 drift |
| Pichardo [53] | 2014 | Multi-baseline MR-based thermometry | Reduced temperature SD from 25.2 to 2.4 °C | B0 changes due to motion |
| Shi [54] | 2014 | partial separability (PS) model and referenceless thermometry introduced | N/A | Feasibility |
| Minalga [55] | 2013 | Integrated multi-channel RF receive coil with MR-HIFU | 163% SNR improvement averaged over all positions investigated | Feasibility |
| Ramsay [56] | 2013 | Segmented GRE-EPI technique | N/A | Feasibility |
| Kickhefel [57] | 2010 | Comparison of fast sequences | Stability improvement from 1.07 to 0.21 °C | Comparison |
| Wyatt [58] | 2010 | Correction of breathing-induced errors using multi-echo fitting methods | Temperature SD from 2.18 to 0.61 °C and bias from 3.17 to −1.26 °C | B0 changes and image gaps due to motion |
| Roujol [59] | 2009 | Reconstruction pipeline for adaptive TSENSE | Image latencies below 90 ms at frame rates up to 40 images/s | Acceleration |
| Wyatt [60] | 2009 | Different stabilization strategies | Improved error by up to 0.5 °C | B0 drift |
| Silcox [61] | 2005 | Ultrasonic heating to control transgene expression spatially using a minimally invasive approach | N/A | Feasibility |
| Sun [62] | 2005 | Adaptive controllers with MRT | N/A | Feasibility |
| Peller [28] | 2002 | Characterize T1 for thermometry | N/A | Feasibility |
| Il’yasov [63] | 1998 | RARE sequence for diffusion MRT | N/A | Feasibility |
| Corbett [64] | 1997 | 1H MR spectroscopy to measure absolute brain temperature | N/A | Feasibility |
| MacFall [65] | 1996 | Chemical shift of water for MRT | N/A | Feasibility |
| De Poorter [66] | 1995 | PRF thermometry in vivo | N/A | Feasibility |
| MacFall [67] | 1995 | Rapid diffusion weighted EPI, being less sensitive to motion | Temperature SD from 1.5 to 0.9 °C | B0 changes due to motion |
| Young [68] | 1994 | Initial investigation of T1 dependence, D and perfusion | N/A | Feasibility |
| Hall [69] | 1990 | Investigation which MR parameter would be best for MRT in vivo | N/A | Comparison |