Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Dec 31;22(1):355. doi: 10.3390/ijms22010355

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

The pattern and intensity of GRP78 positivity coincides with nuclear p53 on immunostaining and is associated with the response to cisplatin-based chemotherapy. (A) Whole biopsies and representative GRP78 and p53 immunostaining of specimens of oral cancers taken before cisplatin-based induction chemotherapy. Dominant p53 nuclear staining coincides with the area of strong GRP78 positivity except for patient #5. (B) The percentage of relative tumor volume change of patients after two courses of induction chemotherapy. Patient #1 shows progression (23%) and patient #7 shows regression (45%) markedly after treatment. Scale bar: 2 and 0.1 mm for 1× and 15×, respectively.