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. 2020 Dec 30;13(1):85. doi: 10.3390/cancers13010085

Figure 6.

Figure 6

Experimental therapy with tumor volume growth curves for individual mice in each group. SKOV3 cells were subcutaneously implanted into the belly of nude BALB/c nu/nu mice. One week later the mice were randomized into four groups and given s.c. injections (scruff of the neck) of either PBS (A), 15.1 mg/kg ZHER2:2891-ABD-E3-AA (B), 10.3 mg/kg ZHER2:2891-ABD-E3-mcDM1 (C), or 15.1 mg/kg ZHER2:2891-ABD-E3-mcDM1 (D). Four injections were given at day 0, 7, 14, and 21. The mice were euthanized when the volume of the subcutaneous xenografts exceeded 1000 mm3 (Δ) or bleeding ulcers on the xenografts were observed (Χ). (E) Survival of the mice during the experimental therapy.