Table 2.
Prognostic Factor | No. of Patients | No. of Clinical Trials | Response Rate | p-Value |
---|---|---|---|---|
Mean % [95% CI] | ||||
Age: | 0.7743 | |||
65 | 483 | 12 | 50.7% [39.1–62.3] | |
>65 | 180 | 5 | 52.6% [24.0–81.1] | |
Lymphodepletion: | 0.4737 | |||
Yes | 835 | 12 | 57.1% [46.9–67.4] | |
No | 13 | 3 | 42.9% [0–100] | |
CAR-T cells infused: | 0.2043 | |||
1 × 107/kg | 442 | 12 | 58.5% [47.0–70.0] | |
>1 × 107/kg | 35 | 5 | 43.4% [5.8–81.0] | |
Cancer type: | ||||
B-ALL | 184 | 5 | 72.3% [60.6–84.1] | |
DLBCL | 490 | 9 | 41.4% [32.6–50.2] | |
FL | 49 | 5 | 52.5% [30.2–74.7] | |
MCL | 73 | 3 | 22.2% [0–100] |