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Population, Intervention, Comparison and Outcome (PICO) Strategy.
| Parameter | In Vitro/In Situ | Clinical |
|---|---|---|
| Population | Teeth or dentin discs | Patients in need of a restoration |
| Intervention | Restoration with prior application of cavity disinfection methods | |
| Comparison | Conventional restoration | |
| Outcome | Effect of cavity disinfection on dentin adhesion (bond strength) | Effect of cavity disinfection on the clinical success of restoration |
