COVID-19	coronavirus disease 2019
SARS	severe acute respiratory syndrome
SARS-CoV-2	severe acute respiratory syndrome coronavirus-2
PHEIC	public health emergency of international concern
S-protein	spike glycoprotein
ACE2	angiotensin-converting enzyme 2
ACE	angiotensin-converting enzyme
RBD	receptor-binding domain
cryo-EM	cryo-electron microscopy
RAS	renin-angiotensin system
Ang I	angiotensin I
Ang II	angiotensin II
AT1	angiotensin receptor type 1
AT2	angiotensin receptor type 2
ACEIs	ACE inhibitors
ARBs	AT1 receptor blockers
ARDS	acute respiratory distress syndrome
ICU	intensive care unit
ADAM-17	ADAM metallopeptidase domain 17
TMPRSS2	Transmembrane Serine Protease 2
AR	androgen receptor
DHT	dihydrotestosterone
LNCaP	activin-sensitive prostate cancer cells
ER	endoplasmic reticulum
hESC	human embryonic stem cell
PD	peptidase domain
NAAE	N-(2-aminoethyl)-1 aziridine-ethanamine
IC50	the half maximal inhibitory concentration
KD	the calculated affinity
IFN	interferon
IL	interleukin
ERK	extracellular signal-regulated kinase
JNK	c-Jun N-terminal kinase
IPF	idiopathic pulmonary fibrosis
PAH	pulmonary arterial hypertension
ALI	acute lung injury
LPS	lipopolysaccharide
TLR4	toll-like receptor 4
MAP	mitogen-activated protein
ERK/MAPK	extracellular-signal-regulated kinase/mitogen-activated protein kinase
NF-κB	nuclear factor-κB
AMPA	alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid
APJ	the apelin receptor
SIRT1	Sirtuin 1
AMPK	AMP-activated protein kinase
T2DM	Type 2 diabetes mellitus
ISG	interferon stimulated gene
fMLP	N-formylmethionyl-leucyl-phenylalanine
MAS1	the G protein-coupled receptor Mas