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. 2020 Dec 28;22(1):236. doi: 10.3390/ijms22010236

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Epigenome Manipulation in Somatic Cell Nuclear Transfer (SCNT): possibilities to improve the outcome of SCNT experiments in the different steps of the procedure. HDACi: histone deacetylase inhibitors; DNMTi: DNA methyl-transferase inhibitors; MECP2: methyl-CpG–binding protein 2; TET3: tet methylcytosine dioxygenase 3; PGC7: primordial germ cell 7; RTL1: retrotransposon Gag like 1; XIST: X inactive specific transcript; H3K27me3: tri-methylation of histone-H3 lysine 27; DUX: double homeobox.