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Dynamic methylation and hydroxymethylation changes at single-nucleoside resolution upon H. hepaticus-induced inflammation in Rag2−/−/Il10−/− mice: (A) pie charts showing the genomic feature distribution of 784 hypo DMRs, 822 hyper DMRs, 1454 hypo DhMRs, and 1557 hyper DhMRs and (B) dynamic change of 5mC and 5hmC at each CpG sites within DMR/DhMR. We considered 0.1 as a cutoff of significant change in the 5mC/5hmC fraction. Numbers represent counts of sites.
