Table 1.
Characterisation of the PitNET TMA cohort, including TGFBR3L.
Tumour Type | Number | IHC Subtype | Clinical Phenotype | TGFBR3L Positive |
---|---|---|---|---|
Gonadotroph | 110 | SF1; FSH/LH | NF-PitNET 1 | 37 |
Corticotroph | 21 | T-Pit; ACTH | Cushing/Nelson | 0 |
25 | T-Pit; ACTH | NF-PitNET 1 | 0 | |
Somatotroph | 24 | Pit-1; GH | Acromegaly | 0 |
31 | Pit-1; GH-PRL | Acromegaly | 0 | |
2 | Pit-1; GH | NF-PitNET 1 | 0 | |
Lactotroph | 6 | Pit-1; PRL | Hyperprolactinemia | 0 |
2 | Pit-1; PRL | NF-PitNET 1 | 0 | |
Thyrotroph | 2 | Pit-1; TSH | HyperTSH | 0 |
Null cell | 7 | TFs 2 neg; Hormone neg. |
NF-PitNET 1 | 0 |
Total | 230 | 37 |
1 NF-PitNet: Non-functioning pituitary neuroendocrine tumour. 2 TF: Transcription factor.