Table 2.

CAC progression according to the quartiles of each parameter in the final cohort including non-progressors and progressors (n = 1145).

Parameter	n	OR (95% CI)
		Unadjusted	Model 1	Model 2	Model 3
HOMA-IR
First quartile	287	1.00 (Ref)	1.00 (Ref)	1.00 (Ref)	1.00 (Ref)
Second quartile	286	1.35 (0.91–1.99)	1.33 (0.89–1.99)	1.27 (0.84–1.92)	1.22 (0.80–1.87)
Third quartile	285	1.48 (1.01–2.18)	1.36 (0.91–2.03)	1.24 (0.82–1.88)	1.24 (0.81–1.90)
Fourth quartile	287	1.52 (1.03–2.23)	1.41 (0.95–2.10)	1.28 (0.83–1.96)	1.22 (0.78–1.89)
TyG
First quartile	286	1.00 (Ref)	1.00 (Ref)	1.00 (Ref)	1.00 (Ref)
Second quartile	286	1.84 (1.24–2.73)	1.67 (1.11–2.52)	1.52 (0.99–2.33)	1.65 (1.06–2.57)
Third quartile	287	1.54 (1.03–2.29)	1.36 (0.90–2.08)	1.20 (0.76–1.91)	1.26 (0.78–2.02)
Fourth quartile	286	1.90 (1.28–2.82)	1.72 (1.14–2.61)	1.43 (0.89–2.30)	1.46 (0.90–2.38)
TyG-BMI
First quartile	286	1.00 (Ref)	1.00 (Ref)	1.00 (Ref)	1.00 (Ref)
Second quartile	287	1.49 (0.99–2.25)	1.26 (0.83–1.93)	1.25 (0.80–1.93)	1.28 (0.81–2.01)
Third quartile	286	2.10 (1.41–3.11)	1.71 (1.13–2.59)	1.55 (1.00–2.45)	1.56 (0.97–2.44)
Fourth quartile	286	2.03 (1.37–3.02)	1.83 (1.21–2.79)	1.68 (1.05–2.69)	1.62 (1.00–2.62)
TyG-WC
First quartile	286	1.00 (Ref)	1.00 (Ref)	1.00 (Ref)	1.00 (Ref)
Second quartile	286	1.80 (1.18–2.74)	1.33 (0.86–2.07)	1.27 (0.80–2.01)	1.20 (0.74–1.93)
Third quartile	287	2.54 (1.69–3.83)	1.92 (1.24–2.96)	1.78 (1.11–2.86)	1.64 (1.01–2.66)
Fourth quartile	286	2.68 (1.78–4.03)	1.96 (1.27–3.03)	1.80 (1.10–2.94)	1.66 (1.01–2.77)

Model 1 was adjusted for age and sex. Model 2 was adjusted for the variables included in model 1, plus systolic BP, LDL-C, HDL-C, smoking, drinking, and exercise habits. Model 3 was adjusted for the variables included in model 2, plus baseline CAC score and follow-up interval. Logistic regression analysis was performed to calculate the odds ratios (ORs) and 95% confidence intervals (CIs) of the subgroups for the prediction of CAC progression.