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. 2020 Dec 28;22(1):212. doi: 10.3390/ijms22010212

Table 1.

Sites, pathogenic mechanisms, and main treatment strategies for the four ophthalmic conditions discussed in this review.

Site Pathogenesis Treatment
Age-related cataract Lens Malfunctioning proteins on lens (Present) removal of the cloudy lens
(Future) antioxidant application
[44]
Glaucoma Optic nerves Ganglion cell degeneration (Present) release of IOP
(Future) neuroprotection
[54]
AMD Retina (macula) Macular degeneration and vascularization (Future) anti-VEGF agents and reversal of angiogenesis [57]
DR Retina Vascular abnormalities (Traditional) laser or surgery
(Future) anti-VEGF agents
[70]

IOP, intraocular pressure.