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. 2020 Dec 31;22(1):374. doi: 10.3390/ijms22010374

Table 1.

The effect of aryl hydrocarbon receptor (AhR) signaling in physiological functions.

Function Effect on the AhR Pathway References
Cell regeneration Activation [23]
Immune reaction Activation [24,25,26]
Intestinal homeostasis Activation [6,25]
Hematopoietic stem cell (HSC) proliferation Inhibition [27]
Skin pathogenesis Inhibition [28]
Neurogenesis and neural precursor cells Activation [2,27]
Retinal homeostasis Activation [29]
Regulation of sex hormones and reproduction Activation [19,30,31]
Embryonic cardiac development Activation [32]
Insulin–glucose regulation Activation [23,32]
Adipocyte differentiation Inhibition [33,34]
Closure of ductus venous Activation [35]
Thickness aorta Inhibition [36]
Movement regulation Inhibition [37]