Table 4.
Differential expression genes involved in the AhR pathway.
| AhR | ARNT | CYP1B1 | AhRR | |
|---|---|---|---|---|
| Septuagenarians vs. Young people | −2.04 (p value = 0.004) |
−1.62 (p value = 0.05) |
−1.46 (p value = 0.04) |
1.34 (p value = 0.01) |
| Centenarians vs. Septuagenarians | 2.37 (p -value = 0.001) |
2.41 (p value = 0.001) |
1.87 (p value = 0.002) |
−1.53 (p value = 0.0008) |
| Centenarians vs. Young people | 1.16 (NC) | 1.49 (NC) | 1.20 (NC) | −1.13 (NC) |
NC = no changes were observed. Negative numbers indicate underexpression compared to the corresponding controls; positive indicates overexpression.