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Data summary and differential analysis. (A) summary of canonical miRNAs, isomiRs, mRNAs, intron-spanning reads and proteins used in this study for subsequent analysis; (B) heatmaps of differentially expressed canonical miRNAs and isomiRs; (C) heatmaps of differentially expressed intron-spanning reads and mRNAs; (D) heatmap of differentially expressed proteins. Significance level was set to p-value < 0.05 and |Log2 FC| > 1.
