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. 2020 Dec 29;13(1):66. doi: 10.3390/cancers13010066

Figure 4.

Figure 4

Validation of miR-29a-3p inhibitory effect on SPARC mRNA expression. (A) Table on previous studies validating the inhibition of SPARC caused by miR-29a-3p. (B) Modulation of SPARC mRNA expression levels after transfection with pre-miR-29a-3p (green) or anti-miR-29a-3p (orange) in LPC006 and Panc-1 cells. (C) Modulation of migration in LPC006 cells after transfection with anti-miR-29a-3p (orange), pre-miR-29a-3p (green) or miR-negative control (blue–dashed line). Significance was assessed with T-Student Test (* p < 0.05, ** p < 0.01, *** p < 0.0001). Dashed line refers to comparative levels in miR-negative controls.