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. 2020 Dec 31;26(1):144. doi: 10.3390/molecules26010144

Figure 1.

Figure 1

Exemplary result of SYN-view. The figure shows two alignments of NGIs throughout the closest relatives of Streptomyces nivues NCIMB 11891 (Table 1). Note that for a clear comparison, only two NGI alignments are shown, while three were found (Supplementary Data). (A) NGI of DNA topoisomerase which is regularly observed in close relatives with the structure of the NGI is well conserved. (B) The NGI of the duplicated, resistant gyrB is unique to the antibiotic producing strain and can easily be distinguished.