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. 2020 Dec 29;13(1):69. doi: 10.3390/cancers13010069

Figure 3.

Figure 3

Fenofibrate diet mitigates the reduction in intra-epidermal nerve fiber (IENF) density at 21 days post-paclitaxel injection. (a) Quantification of IENF density in hind paw skin at day 21 post-treatment. (b) Immunostained sections of Regular-diet/Veh, Regular-diet/Paclitaxel, Fenofibrate diet 0.2%/Paclitaxel and Fenofibrate diet 0.4%/Paclitaxel hind paw skin showing the lENFs. Values are expressed as mean ± SEM. n = 10/group. Results were compared using two-way or one-way ANOVA with post-hoc Tukey’s test and t-test (*: p < 0.05 vs. vehicle). D = day; Feno = Fenofibrate; Reg = Regular; PAC = paclitaxel; Veh = Vehicle. No sex differences were observed (data not shown).