Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Cell death in renal ischemia/reperfusion injury (IRI). Groups of mice (n = 10) were treated with vehicle, 10 or 30 mg/kg/BID GS-642462 and compared to sham controls (n = 6). (A–C) TUNEL staining. (A) Sham control lacks TUNEL+ cells. (B) Vehicle-treated IRI showing many TUNEL+ tubular cells in the outer medulla. (C) IRI treated with 30 mg/kg GS-642362 shows a marked reduction in the number of TUNEL+ cells. Bar = 100 µm. (D) Graph of TUNEL+ cells.
