IMPase |
inositol-monophosphatase |
IPPase |
inositol polyphosphate-1-phosphatase |
GSK-3 |
glycogen-synthase-kinase-3 |
AD |
Alzheimer’s disease |
CNS |
central nervous system |
HD |
Huntington’s disease |
ALS |
amyotrophic lateral sclerosis |
sALS |
sporadic ALS |
fALS |
familial ALS |
FTLD |
frontotemporal lobar dementia |
PD |
Parkinson’s disease |
INNs |
intraneuronal nuclear inclusions |
HTT |
huntingtin gene |
CAG |
cytosine–adenine–guanine |
SNpc |
substantia nigra pars compacta |
LBs |
Lewy bodies |
CMA |
chaperone-mediated autophagy |
MS |
Multiple sclerosis |
RRMS |
relapsing-remitting |
SPMS |
secondary progressive phase |
PPMS |
primary progressive disease |
APP |
amyloid-precursor protein |
Aβ |
amyloid beta |
FDA |
food and drug administration |
IP3 |
inositol triphosphate |
DAG |
diacylglycerol |
PHFs |
paired helical filaments |
Ach |
acetylcholine |
AChE |
acetylcholinesterase |
AChE-S |
synaptic AChE |
AChE-R |
readthrough acetylcholinesterase |
TBI |
traumatic brain injury |
BACE-1 |
β-secretase-1 |
PP2A |
protein phosphatase 2A |
PS1 |
presenilin-1 |
LiPQQ |
tri-lithium pyrroloquinoline quinone |
ABAD |
β-amyloid-binding alcohol dehydrogenase |
CREB1 |
cyclic AMP responsive element binding protein 1 |
CRTC1 |
transcriptional coactivator for CREB1 |
Bace1 |
β-site APP cleaving enzyme-1 |
CSF |
cerebrospinal fluid |
BDNF |
brain-derived neurotrophic factor |
GDNF |
glial cell-derived neurotrophic factor |
PKC |
protein kinase C |
NDI |
nephrogenic diabetes insipidus |
CKD |
chronic kidney disease |
ESKD |
end-stage kidney disease |
LRP1 |
lipoprotein receptor-related protein 1 |