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. 2021 Jan 1;13(1):117. doi: 10.3390/cancers13010117

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Serum levels and IHC scores of vascular endothelial growth factor (VEGF-A), vascular endothelial growth factor receptor 1 (VEGFR-1) and receptor 2 (VEGFR-2) in tumor infiltrating lymphocytes (TILs) of cats with mammary carcinoma. (A) Cats with tumors and a positive score for TILs showed higher serum VEGF-A, (B) VEGFR-1 and (C) VEGFR-2 levels in comparison with cats that showed a negative score for TILs. (D) Box plot diagrams showing that queens with mammary carcinomas scored as VEGFR-2-positive TILs had high serum VEGF-A and (E) VEGFR-1 levels.