Table 3.

The MDDR-DS3 structure activity classes.

Activity Class	Active Molecules	Activity Index
Muscarinic (M1) agonists	900	09,249
NMDA receptor antagonists	1400	12,455
Nitric oxide synthase inhibitors	505	12,464
Dopamine β-hydroxylase inhibitors	106	31,281
Aldose reductase inhibitors	957	43,210
Reverse transcriptase inhibitors	700	71,522
Aromatase inhibitors	636	75,721
Cyclooxygenase inhibitors	636	78,331
Phospholipase A2 inhibitors	617	78,348
Lipoxygenase inhibitors	2111	78,351