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. 2020 Dec 30;22(1):297. doi: 10.3390/ijms22010297

Figure 3.

Figure 3

NF-E2-related factor 2 (Nrf2) and heme oxygenase-1 (HO-1) expression in the retina. (A) Immunoreactivities of Nrf2 and RNA-binding protein with multiple splicing (RBPMS). (B) Immunoreactivities of HO-1 and RBPMS. (C) Quantitative comparison of the immunoreactivities of Nrf2 and HO-1 in RGCs and the inner plexiform layer (IPL). DMF was administered orally at a concentration of 100 mg/kg. Each circle denotes the individual estimated values based on nine different retinal images (three different images from each animal). Asterisks indicate p < 0.05 (n = 9 each) compared to ONC with the vehicle (unpaired t-test). Scale bar = 50 μm.