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. 2020 Dec 28;26(1):96. doi: 10.3390/molecules26010096

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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[^99mTc]Tc-Gluconate and [^99mTc]Tc-DTPA imaging of an ischemia reperfusion mouse model. BALB/c mice received 3 h of tourniquet-induced ischemia modeling after 3 h of reperfusion (yellow triangle). Thereafter, 12 MBq of (A) [^99mTc]Tc-gluconate or (B) [^99mTc]Tc-DTPA was intravenously injected via tail vein. After 1 h, legs were imaged by SPECT/CT. (C) Average standard uptake value (SUV) representing uptake in both normal and ischemic limbs. Statistical significance was determined using an unpaired Student’s t-test. ** p < 0.05, *** p < 0.01.

[^99mTc]Tc-Gluconate and [^99mTc]Tc-DTPA imaging of an ischemia reperfusion mouse model. BALB/c mice received 3 h of tourniquet-induced ischemia modeling after 3 h of reperfusion (yellow triangle). Thereafter, 12 MBq of (A) [^99mTc]Tc-gluconate or (B) [^99mTc]Tc-DTPA was intravenously injected via tail vein. After 1 h, legs were imaged by SPECT/CT. (C) Average standard uptake value (SUV) representing uptake in both normal and ischemic limbs. Statistical significance was determined using an unpaired Student’s t-test. ** p < 0.05, *** p < 0.01.