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. 2021 Jan 1;26(1):181. doi: 10.3390/molecules26010181

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Effect of ECN on DNA damage in the sciatic nerve and spinal cord tissues analysed by comet assay. Fluorescence photomicrographs exhibiting the protective effect of ECN against PSNL induced DNA damage in (A) sciatic nerve and (B) spinal cord. (C) DNA content is estimated by tail length and % DNA in the tail in the PSNL experiment. The data is presented as the mean (n = 5) ± S.D. Different letters meant statistically significant differences: (***) p < 0.001 indicate significant differences from the PSNL control group. (###) indicate significant differences from the normal control group. *** p < 0.001 (one-way ANOVA followed by Bonferroni post-test).

Effect of ECN on DNA damage in the sciatic nerve and spinal cord tissues analysed by comet assay. Fluorescence photomicrographs exhibiting the protective effect of ECN against PSNL induced DNA damage in (A) sciatic nerve and (B) spinal cord. (C) DNA content is estimated by tail length and % DNA in the tail in the PSNL experiment. The data is presented as the mean (n = 5) ± S.D. Different letters meant statistically significant differences: (***) p < 0.001 indicate significant differences from the PSNL control group. (###) indicate significant differences from the normal control group. *** p < 0.001 (one-way ANOVA followed by Bonferroni post-test).