T1D |
Type 1 diabetes |
MHC-II |
Major histocompatibility class II |
SCFA |
Short-chain fatty acid |
Treg |
T regulatory cells |
TCR |
T cell antigen receptor |
IGRP-reactive CD8+ T cells |
Islet-specific glucose-6-phosphatase catalytic subunit–related protein (IGRP) reactive CD8 T cell |
LPS |
Lipopolysaccharide |
IAA |
Insulin autoantibody |
GADA |
Glutamic acid decarboxylase antibody |
FOXP3 |
Forkhead box P3 |
HDACi |
Histone deactylase inhibitor |
HMGB1 |
High-mobility group protein 1 |
NF-κB p65 |
Nuclear factor kappa-light-chain-enhancer of activated B cells |
mTOR complex |
Mammalian target of rapamycin complex |
HATs |
Histone acetyltransferases |
PSA |
Polysaccharide A |
TEDDY |
The Environmental Determinants of Diabetes in the Young |
Rorc |
RAR-related orphan receptor C gene |
Stat3 transcription factor |
Signal transducer and activator of transcription 3 |
TGF-β gene |
Transforming growth factor β gene |
TGF-β |
Transforming growth factor β |
ATRA |
Alltrans retinoic acid |
INS |
Insulin gene 3 |
PTPN-22 |
Protein tyrosine phosphatase non-receptor type 22 gene |
CTLA4 |
Cytotoxic T-lymphocyte-associated protein 4 gene |
IL2RA |
Interleukin 2 receptor alpha |
IFIH1 |
Interferon-induced with helicase C domain 1 |
CDHR5 |
Cadherin-related family member 5 |
CDH1 |
Cadherin-1 |
FCGBP |
IgGFc-binding protein |
CEACAM5 |
Carcinoembryonic antigen-related cell adhesion molecule 5 |
MUC2 |
Mucin-2 |
MGAM |
Maltase-glucoamylase |
NAALADL1 |
N-acetylated alpha-linked acidic dipeptidase like 1 |
PXK |
PX domain-containing protein kinase-like protein |
PDHB |
Pyruvate Dehydrogenase E1 Subunit Beta |
PPIL2 |
Peptidylprolyl Isomerase Like 2 |