Table 1.

Main advantages and disadvantages of metal-based nanoparticles (NPs).

	Advantages	Disadvantages
Metal-Based NPs	Biocompatibility High oxidation efficacy High photostability High binding affinity Low cost Surface enhanced Raman scattering Strong plasma absorption Biological system imaging Determine chemical information on metallic nanoscale substrate	Instability Impurities loaded during their synthesis Difficulty in synthesis Thermal decomposition