Figure 4.

Comparing the free energy $F^{*}(N_c,I_c)$ for different choices of model parameters, Scale 0, 1, 2 as indicated in Table 1, at fixed concentration $c=11\%$, and ambient temperature (top row) or warmer temperature (bottom row). Axes and colors are as in Figure 3. Under these conditions, $F^{*}(N_c,I_c)$ for Scale 0 (left) has a minimum corresponding to folded proteins (FOL). For Scale 1 (center), at ambient temperature (top), the proteins are unfolded and aggregated (AGG), while at the higher temperature (bottom), they unfold (UNF) but have a small tendency to aggregate. For Scale 2 (right), at both temperatures, the proteins aggregate (AGG) and are more unfolded at the lower temperature.