| ICP | immune checkpoint |
| mAb | monoclonal antibody |
| CTLA-4 | cytotoxic T lymphocyte associated protein-4 |
| PD-1 | programmed deat-1 |
| TIL | tumor-infiltrating lymphocyte |
| irAEs | immune-related adverse events |
| LAG-3 | lymphocyte activating gene-3 |
| TME | tumor microenvironment |
| IHC | immunohistochemistry |
| Ig | immunoglobulin |
| MHC-II | major histocompatibility complex |
| pMHC-II | peptide loaded MHC-II |
| APC | antigen-presenting cell |
| Gal-3 | galectin-3 |
| LSECtin | liver sinusoidal endothelial cell lectin |
| FGL-1 | fibrinogen like protein 1 |
| IFN-γ | Interferon gamma |
| IL | Interleukin |
| Treg | regulatory T cell |
| NK | natural killer cell |
| pDC | plasmacytoid dendritic cell |
| DC | dendritic cell |
| TAM | tumor-associated macrophage |
| TOX | thymocyte selection-associated high mobility group box protein |
| NFAT | nuclear factor of activated T cells |
| NR4A | nuclear receptor subfamily 4, group A |
| TGF-β | transforming growth factor beta |
| EGR2 | early growth response gene 2 |
| ITIM | immunoreceptor tyrosine-based inhibitory motifs |
| LAP | LAG-3-associated protein |
| NSCLC | non-small-cell lung cancer |
| sLAG-3 | soluble LAG-3 |
| OS | overall survival |
| Zr89 | Zirconium89 |
| Fab | antigen binding fragment |
| scFv | single-chain variable fragment |
| TNF-α | tumor necrosis factor alpha |