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The ability of individual CST variants to restore sialylation of N- and O-glycans in the knock-out cells: (-), no rescue; (+), little rescue; (++), moderate rescue; (+++), full rescue.
| CST Variant | N-Glycans | O-Glycans |
|---|---|---|
| Wild-type | +++ | +++ |
| Q101H | - | +++ |
| T156R | ++ | +++ |
| E196K | ++ | + |
| T156R/E196K | - | + |
