TiO2	Titanium dioxide
BuRO	Dutch Office for Risk Assessment and Research
AOP	Adverse Outcome Pathway
EU	European Union
IARC	International Agency for Research and Cancer
RAC	Risk Assessment Committee
ECHA	European Chemical Agency
CLP	Classification, Labelling and Packaging
ROS	Reactive Oxygen Species
EFSA	European Food Safety Authority
ANSES	French Agency for Food, Environmental and Occupational Health
NVWA	Netherlands Food and Consumer Products Safety Authority
TEM	Transmission Electron Microscopy
Sp-ICP-MS	Single Particle Inductively Couple Plasma Mass Spectrometry
LPS	Lipopolysaccharides
NF-kB	Nuclear Factor Kappa Light-Chain-Enhancer of activated B-cell
IRF-3	Interferon Regulatory-Factor 3
Bw	Body weight
TJ	Tight junction
PBPK	Physiologically Based Pharmacokinetics
TEM-EDX	Transmission Electron Microscopy -Energy Dispersive X-Ray Analysis
IFN-γ	Interferon-gamma
TNF-⍺	Tumor Necrosis Factor alpha
ALP	Alkaline Phosphatase
ALT	Alanine Aminotransferase
ASP	Aspartate Aminotransferase
GSH	Glutathione
GSSG	Glutathione Disulfide
GPx	Glutathione Peroxidase
SOD	Superoxid Dismutase
CAT	Catalase
IL	Interleukin
CYP450	Cytochrome P450
COX-2	Cyclooxygenase-2
Ki67	Antigen Ki67
Th-1	T-helper-1
P65	Transcription factor p65
MAPK	Mitogen-Activated Protein Kinase
GPCR	G-Protein Coupled Receptor
ER	Endoplasmic Reticulum
I.V.	Intravenous
I.P.	Intraperitoneal
IBD	Inflammatory Bowel Disease
CRC	Colorectal Cancer
BBB	Brain-Blood-Barrier
NO	Nitric Oxide
GT	Glutamyltransferase
StAR	Steroidogenic Regulatory Protein
BCL-2	B-cell Lymphoma-2
MAD	Malondialdehyde
PSA	Prostate-Specific Antigen
OECD	Organization for Economic Cooperation and Development
GR	Glutathione Reductase
LC-3	1A/1B-Light-Chain-3
ERK	Extracellular Signaling Regulated Kinase
BAX	Bcl-2-Associated X protein
Apaf-1	Apoptotic Peptidase Activating Factor 1
Nrf2	Nuclear Factor Erythroid 2-related Factor 2
IE	Initiating Event
KE	Key Event
PAMP	Pathogen-Associated-Molecular-Pattern
ATP	Adenosine Triphosphate
KEGG	Kyoto Encyclopedia of Genes and Genomes
EGFR	Epidermal Growth Factor Receptor
Cdk2	Cyclin Dependent Kinase 2
TfEB	Transcriptional Factor EB
GLP	Good Laboratory Practice
T/SEM	Transmission/Scanning Electron Microscopy
DLS	Dynamic Light Scattering
NTA	Nanoparticle Tracking Analysis
FCS	Fluorescence Correlation Spectroscopy