HFD |
High-fat diet |
SD |
Standard diet |
RWAT |
Retroperitoneal white adipose tissue |
EWAT |
Epididymal white adipose tissue |
H&E |
Hematoxylin and eosin |
ALT |
Alanine aminotransferase |
AST |
Aspartate aminotransferase |
FABP4 |
Fatty acid-binding protein 4 |
SREBP1 |
Sterol regulatory element-binding protein 1 |
FASN |
Fatty acid synthase |
PNPLA3 |
Patatin-like phospholipid domain containing protein 3 |
AUC |
Area under the curves |
IR |
Insulin resistance |
IS |
Insulin sensitivity |
HOMA |
Homeostatic model assessment |
GLUT |
Glucose transport |
BUN |
Blood urea nitrogen |
GPx |
Glutathione peroxidase |
SOD |
Superoxide dismutase |
ERK |
Extracellular signal-related kinase |
SOCS |
Suppressor of cytokine signaling |
FGF-21 |
Fibroblast growth factor-21 |
NLRP3 |
Leucine-rich repeat domain containing 3 |
IL-1β |
Interleukin-1β |
IL-18 |
Interleukin-18 |
IPGTT |
Intraperitoneal glucose tolerance test |
TNF-β |
Tumor necrosis factor-β |
IHC |
Immunohistochemical |