Forest plots showing the pooled estimate of (A) incidence rate ratio of ORR and (B) incidence rate ratio of DCR according to RECIST 1.1 and iRECIST. The pooled incidence rate ratio of ORR per RECIST 1.1 and iORR per iRECIST is 0.97 (95% CI, 0.90–1.03), and the pooled incidence rate ratio of DCR per RECIST 1.1 and iDCR per iRECIST is 0.96 (95% CI, 0.91–1.01), indicating no significant increase in both ORR and DCR using iRECIST compared with RECIST 1.1. “i” indicates immune responses assigned using iRECIST. Abbreviations: CI, confidence interval; CR, complete response; DCR, discase control rate; IRR, incidence rate ratio; ORR, overall response rate; PR, partial response; SD, stable disease.