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Representative photomicrographs of calvaria defect after 3 month. Histological section stained with hematoxylin/eosin from the region of control without biomaterial (A,B), biomaterial implantation in the PLA (C,D), PLA-CaP (E,F) and PLA-CaP-rhBMP-2 (G,H) groups—3 month after implantation. The region occupied by pre-existing bone is indicated with (PEB), newly formed bone (NFB); connective tissue (CT) and biomaterial/PLA scaffold (BM). Results are representative of 5 rat/group.
