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. 2020 Dec 24;22(1):124. doi: 10.3390/ijms22010124
AEX Anion exchange
AP Alkaline phosphatase
aTc Anhydrotetracycline hydrochloride
AUC Area und the curve
BCIP 5-Bromo-4-chloro-3-indoxyl phosphate
BSA Bovine serum albumin
CEX Cation exchange
CL Clearance
Cmax Maximum (or peak) serum concentration
CNP C-type natriuretic peptide
CORYNEX Corynebacterium glutamicum protein expression system
COVID-19 Severe acute respiratory syndrome coronavirus 2
CTLA-4 Cytotoxic T-lymphocyte-associated protein 4
CV Column volume
DCs Dendritic cells
DPP-IV Dipeptidyl peptidase-4
ELISA Enzyme-linked immunosorbent assay
ESETEC E. coli secretion technology
ESI-MS Electrospray ionization mass spectrometry
FPLC Fast protein liquid chromatography
GCC Glucagon
GIP Glucose-dependent insulinotropic polypeptide
GLP-1 Glucagon-like peptide 1
GM-CSF Granulocyte-macrophage colony-stimulating factor
GSH γ-L-Glutamyl-L-cysteinyl-glycine
HBV Hepatitis B virus
HCV Hepatitis C virus
hGH Human growth hormone
hIFN-α Human interferon 1
HIV-1 Human immunodeficiency virus I
iRGD Internalizing arginylglycylaspartic acid peptide
K3-EDTA Tri-potassium ethylenediaminetetraacetic acid
MHC Major histocompatibility complex
MOPS 3-(N-morpholino)propanesulfonic acid
NBT Nitro blue tetrazolium
OD Optical density at 550 nm
PAS Proline/alanine-rich sequence
PAS-Tα1 N-terminally PASylated Tα1
PBS Phosphate-buffered saline
PD Pharmacodynamics
PEG Polyethylene glycol
p.i. Post injection
PK Pharmacokinetics
ProTα Prothymosin alpha
PTH Parathyroid hormone
Q-TOF Quadrupole time of flight
RBS Ribosome-binding site
RGD Arginylglycylaspartic acid
RimJ Ribosomal-protein-S5-alanine N-acetyltransferase
RPC Reverse phase chromatography
RT Room temperature
SEC Size exclusion chromatography
SDS-PAGE Sodium dodecyl sulfate polyacrylamide gel electrophoresis
τ1/2α Half-life of distribution
τ1/2β Elimination half-life
Tα1 Thymosin alpha 1
Tα1-PAS C-terminally PASylated Thymosin alpha 1
tetp/o Tetracycline promoter/operator
Th T helper cell
tlpp Lipoprotein terminator
TLR-2 Toll-like receptor 1
TLR-9 Toll-like receptor 2
TMAE Trimethylaminoethyl
tmax Time to reach Cmax