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. 2020 Dec 24;22(1):99. doi: 10.3390/ijms22010099

Figure 2.

Figure 2

Post-stroke recovery is worse in isolated aged female mice compared to pair-housed mice. (A) Repeated open field analysis revealed that SI mice (red) had slower recovery compared to PH mice (grey). Although the SI mice showed no significant difference compared to PH mice, on day 14, the PH mice had a trend towards better locomotor activity compared to the SI mice (n = 12–13/group). (B) SI mice (red) also showed an increase in latency in the adhesive tape removal time compared to PH mice (grey) on day 14. (n = 12–13/group; * p = 0.020 at day 7, ** p = 0.005 at day 14 (C) The SI mice had a lower percentage of complete alteration in the Y-maze compared to the PH mice). ST-PH mice had significantly more% correct alterations compared to ST-SI mice (n = 12–13/group; * p = 0.05). Data are presented as mean ± SEM. Repeated two-way ANOVA was used to account for within-subject correlation for the repeated measures (A and B). Student’s t-test was used for group comparisons (C).