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. 2020 Dec 27;22(1):186. doi: 10.3390/ijms22010186
ACC Acetyl-CoA carboxylase
ADaM Allosteric drug and metabolite (binding site on AMPK heterotrimer)
AICA 5-aminoimidazole-4-carboxamide
α-AID Autoinhibitory domain of the AMPK-α subunit
AMPK AMP-activated protein kinase
ARK AMPK-related kinase
ASA Acetyl salicylic acid
ATIC Human gene encoding both AICAR transformylase and IMP cyclohydrolase
ATM Serine-protein kinase ATM (Ataxia telangiectasia mutated)
CaMKI Calmodulin-dependent kinase-I
CaMKK2 Ca2+/calmodulin-dependent kinase kinase-2 (-β)
β-CBM Carbohydrate-binding module of the AMPK-β subunit
CBS Cystathionine β-synthase (refers to CBS domain or CBS repeat)
CBS1 CBS repeat 1; refers to an adenine nucleotide-binding site on the AMPK-γ subunit
CBS3 CBS repeat 3; refers to an adenine nucleotide-binding site on the AMPK-γ subunit
CBS4 CBS repeat 4; refers to an adenine nucleotide-binding site on the AMPK-γ subunit
C-lobe C-terminal lobe of a kinase domain
CSCs Cancer stem cells
α-CTD C-terminal domain of the AMPK-α subunit
β-CTD C-terminal domain of the AMPK-β subunit
EXO1 Exonuclease 1
FBP Fructose-1,6-bisphosphate
GHSR1 Growth hormone secretagogue receptor-1
IGF-1 Insulin-like growth factor-1
IP3 Inositol-1,4,5-triphosphate
iPSCs Inducible pluripotent stem cells
α-KD Kinase domain of the AMPK-α subunit
KO Knockout
LCFA Long chain fatty acid
α-linker Linker region of the AMPK-α subunit
LKB1 Liver kinase B-1
MAGE Melanoma antigen gene (a gene family)
MEFs Mouse embryonic fibroblasts
MO25 Mouse protein 25
mTORC1 mammalian (or mechanistic) target-of-rapamycin complex-1
NES Nuclear exclusion sequence
N-lobe N-terminal lobe of a kinase domain
NLS Nuclear localization sequence
NOTCH1 Neurogenic locus notch homolog protein 1
OCT1 Organic cation transporter 1
PPP1R3C Human gene encoding a glycogen-targetting regulatory subunit of protein phosphatase-1
PRKAA1 Human gene encoding AMPK-α1
PRKAA2 Human gene encoding AMPK-α2
PRKAB1 Human gene encoding AMPK-β1
PRKAG1 Human gene encoding AMPK-γ1
PRKAG2 Human gene encoding AMPK-γ2
PRKAG3 Human gene encoding AMPK-γ3
PTEN Phosphatase and tensin homolog protein
shRNA Short hairpin RNA
siRNA Small interfering RNA
STRAD Ste20-related adaptor
STK11 Human gene encoding LKB1
ST loop Serine/threonine-rich regulatory loop near the C-terminus of the AMPK-α subunit
T-ALL T cell acute lymphoblastic leukameia/lymphoma
TCGA The Cancer Genome Atlas
TRIM-28 Tripartite motif containing 28 (ubiquitin E3 ligase)
UBE2O E2/E3 hybrid ubiquitin-protein ligase
VEGF Vascular endothelial cell growth factor
ZMP 5-aminoimidazole-4-carboxamide ribonucleoside monophosphate