Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Jan 4;13(1):136. doi: 10.3390/cancers13010136

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Physicochemical properties of UA nanoparticles (UA-NP). (A) Field emission scanning electron microscopy (FESEM) photograph of non-formulated UA (magnification: 4000×; scale bar = 10.0 μm). (B) FESEM photograph of nanoformulated UA (magnification: 50,000×; scale bar = 1.0 μm). (C) X-ray diffraction patterns of UA, polyvinylpyrrolidone (PVP), nanoformulated UA nanoparticles (UA-NP), and UA-PVP physical mixture (UA-PM). XRD patterns were taken from 2° to 50° with a scanning rate of 4°/min. The spectra were offset for clarity. (D) Drug dissolution test (open circle, UA-NP; filled circle, UA). Samples containing 4.68 mg equivalent of UA were placed in 100 mL of pH 7.4 phosphate buffer and maintained at 37 ± 0.5 °C. During the dissolution process, samples were withdrawn at 0, 1, 10, 20, 30, 60, 90 and 120 min for HPLC analysis. Data points are expressed as means ± SD (n = 6).