Table 3.
The cell cycle distribution in MCF-7 cells after sumac treatment.
| Time (h) | 24 | 48 | 72 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Treatment | CONT | DMSO | SUM | CONT | DMSO | SUM | CONT | DMSO | SUM |
| Sub-G0/G1 | 0.77 ± 0.03 | 1.14 ± 0.38 | 1.30 ± 0.20 | 1.23 ± 0.01 | 1.09 ± 0.02 | 1.95 ± 0.11 | 1.54 ± 0.13 | 1.42 ± 0.41 | 23.30 ± 3.18 ** |
| G1 | 60.00 ± 3.43 | 53.35 ± 1.59 * | 66.80 ± 1.96 * | 68.50 ± 1.47 | 64.75 ± 1.84 | 66.55 ± 0.20 | 75.15 ± 0.78 | 70.45 ± 0.45 | 49.55 ± 0.12 ** |
| S | 19.45 ± 1.51 | 22.20 ± 1.80 | 18.35 ± 0.04 | 15.40 ± 0.16 | 14.25 ± 1.10 | 15.40 ± 1.06 | 11.65 ± 0.69 | 12.40 ± 0.73 | 17.65 ± 0.53 |
| G2/M | 19.80 ± 1.88 | 23.30 ± 3.02 | 13.55 ± 1.84 * | 14.90 ± 1.63 | 19.90 ± 0.73 | 16.10 ± 1.14 | 11.66 ± 0.04 | 15.75 ± 0.12 | 9.50 ± 2.54 |
The cell cycle distribution in MCF-7cells after SUM treatment (155 µg/mL) was assessed by flow cytometry. Data are expressed as mean ± SD of three independent experiments. The significant differences between control and SUM-treated cells were signed as * p < 0.05, ** p < 0.01.