Table 4.
The cell cycle distribution in MDA-MB-231 cells after sumac treatment.
| Time (h) | 24 | 48 | 72 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Treatment | CONT | DMSO | SUM | CONT | DMSO | SUM | CONT | DMSO | SUM |
| Sub-G0/G1 | 0.58 ± 0.09 | 0.74 ± 0.09 | 2.02 ± 0.16 | 0.69 ± 0.02 | 0.91 ± 0.05 | 4.35 ± 0.35 | 0.98 ± 0.02 | 0.99 ± 0.06 | 4.79 ± 0.31 * |
| G1 | 56.30 ± 0.49 | 58.20 ± 0.73 | 66.55 ± 1.96 * | 62.30 ± 1.06 | 61.65 ± 1.18 | 64.20 ± 0.08 | 68.60 ± 2.04 | 66.75 ± 0.20 | 62.55 ± 0.35 * |
| S | 19.75 ± 0.45 | 18.95 ± 1.51 | 21.65 ± 0.37 | 17.20 ± 0.57 | 16.50 ± 0.98 | 25.30 ± 0.01 * | 11.90 ± 0.33 | 14.55 ± 0.53 | 20.45 ± 2.00 * |
| G2/M | 23.35 ± 0.04 | 22.10 ± 0.90 | 9.80 ± 0.08 * | 19.80 ± 0.49 | 20.90 ± 0.16 | 6.16 ± 0.13 * | 18.50 ± 2.37 | 17.70 ± 0.41 | 12.20 ± 0.16 * |
The cell cycle distribution in MDA-MB-231cells after SUM treatment (215 µg/mL) was assessed by flow cytometry. Data are expressed as mean ± SD of three independent experiments. The significant differences between control and SUM-treated cells were signed as * p < 0.05.