Table 6.
FC analyses of apoptosis induction in MCF-7 cells after SUM (215 µg/mL) treatment.
| Time (h) | 24 | 48 | 72 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Treatment | CONT | DMSO | SUM | CONT | DMSO | SUM | CONT | DMSO | SUM |
| An−/PI− | 92.20 ± 1.22 | 92.40 ± 0.41 | 83.65 ± 1.21 * | 90.90 ± 0.41 | 89.95 ± 0.86 | 75.30 ± 2.61 ** | 89.95 ± 1.67 | 91.65 ± 1.27 | 50.00 ± 3.69 ** |
| An+/PI− | 2.87 ± 0.59 | 2.82 ± 0.18 | 4.25 ± 0.53 | 2.51 ± 0.18 | 3.08 ± 0.33 | 6.92 ± 3.09 | 1.85 ± 0.62 | 2.20 ± 0.98 | 6.22 ± 1.82 |
| An+/PI+ | 3.25 ± 0.36 | 3.01 ± 0.27 | 8.38 ± 1.12 * | 4.06 ± 0.10 | 4.08 ± 0.05 | 12.30 ± 0.16 * | 4.78 ± 0.60 | 3.71 ± 0.53 | 34.00 ± 2.10 ** |
| An−/PI+ | 1.69 ± 0.31 | 1.78 ± 0.05 | 3.75 ± 0.58 | 2.56 ± 0.34 | 2.86 ± 0.48 | 5.46 ± 0.32 | 3.46 ± 0.44 | 2.42 ± 0.22 | 9.78 ± 0.92 * |
Legend: An−/PI− (lower left quadrant; non-apoptotic population), An+/PI− (lower right quadrant; early apoptotic population), An+/PI+ (upper right quadrant; late apoptotic population), An−/PI+ (upper left quadrant; necrotic population). The average of three independent experiments (±SD) is presented. Significances: control vs. SUM-treated cells * p < 0.05, ** p < 0.01.