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. 2021 Jan 2;13(1):123. doi: 10.3390/cancers13010123

Table 2.

A summary of biocomponents found in FTIR and Raman spectra of cellular compartments. ↑↑—high content; —content present or similar but lower than in ↑↑; —low content.

Biocomponent HCV-29 Ta—T24a Ta—T24p T1-RT4 T2—HT-1376 T3—J82
Nucleus
Lipid content (FTIR) ↑↑ ↑↑
Elongated acyl chains (FTIR) ↑↑ ↑↑ ↑↑ ↑↑
Free fatty acids (FTIR)
Phospholipids (RS) ↑↑ ↑↑
Cholesterol and its esters (RS) ↑↑ ↑↑
Protein content (FTIR)
Tyr (RS)
Uroplakin
Protein crosslinking (RS) ↑↑
S-S bridge (RS) ↑↑ ↑↑
DNA content (FTIR)
Glycogen (FTIR)
Carbohydrates (RS) ↑↑ ↑↑ ↑↑
Cytoplasm
Lipid content (FTIR/RS)
Esterified fatty acids and cholesterol (FTIR)
Unsaturated fatty acids (RS) ↑↑ ↑↑
Phospholipids (RS) ↑↑
Protein content (FTIR)
Cytochromes (RS) ↑↑ ↑↑
S-S bridge (RS) ↑↑ ↑↑ ↑↑
Carbohydrates (RS) ↑↑
Graininess
Lipid content (FTIR) ↑↑ ↑↑
Esterified fatty acids and cholesterol (FTIR)
Protein content (FTIR) ↑↑ ↑↑
Glycogen (FTIR)
Sugar moieties (FTIR; 1052 cm−1) ↑↑
Nucleic acids (FTIR) ↑↑
RNA (FTIR)
Lipid droplets
Unsaturated fatty acids (RS) ↑↑
Gauche conformation of acyl chains (RS)
Phospholipids (RS)
Cholesterol and its esters (RS) ↑↑
S-S bridge (RS) ↑↑
Cytochromes (RS) ↑↑
Carbohydrates (RS) ↑↑