AEs	adverse effects
APC	antigen-presenting cell
CCL	C-C motif chemokine ligand
CCR-2	C-C chemokine receptor type 2
CPS	combined positivity score
CR	complete response
CTL	cytotoxic T cells
CTLA-4	cytotoxic T-lymphocyte-associated protein 4
CXCL	C-X-C motif chemokine ligand
DCs	dendritic cells
dMMR	deficient mismatch repair
DOI	depth of invasion
DSS	disease-specific survival
dVIN	differentiated vulvar intraepithelial neoplasia
EMPD	extramammary Paget’s disease
FDA	Food and Drug Administration
FIGO	International Federation of Gynecology and Obstetrics
FOXP3	forkhead box P3
HIF-1α	hypoxia-inducible factor-1α
HLA	human leukocyte antigen
HPF	high-power field
HPV	human papilloma virus
ICI	immune checkpoint inhibitor
IDO	indoleamine 2,3-dioxygenase
IL	interleukin
ILR	interleukin receptor
INF-γ	interferon-γ
iNOS	inducible nitric oxygen synthase
LCs	Langerhans cells
Lm-LLO	Listeria monocytogenes-listeriolysin lipopolysaccharide
LPS	lipopolysaccharide
MAGE-A	melanoma-associated antigen
MAPK	mitogen-activated protein kinase
MHC	major histocompatibility complex
MMR	mismatch repair
MMP-9	matrix-metalloproteinase 9
mPFS	median progression-free survival
MSCs	myeloid-derived suppressor cells
NET	neuroendocrine tumor
MSI-h	microsatellite instability-high
NF-kB	nuclear aactor kappa-light-chain-enhancer of activated B cells
NK	natural killer
NKT	natural killer T cells
NY-ESO-1	New York esophageal squamous cell carcinoma 1
ORR	objective response rate
OS	overall survival
PAMPs	pathogen-associated molecular patterns
PD	progression disease
PD-1	programmed death-1
PD-L1	programmed death-ligand 1
PD-L2	programmed death-ligand 2
PFS	progression-free survival
PR	partial response
PRRs	pattern-recognition receptors
RANK	receptor activator of nuclear factor kappa-Β
Rb	retinoblastoma
RECIST	Response Evaluation Criteria in Solid Tumours
ROS	reactive oxygen species
RFS	recurrence-free survival
RT	radiotherapy
SD	stable disease
SEER	Surveillance, Epidemiology and End Results
SLP	synthetic long peptide
STAT3	signal transducer and activator of transcription 3
TAMs	tumor-associated macrophages
TGF-β	transforming growth factor-β
TH	T helper
TH1	T helper 1
TH2	T helper 2
TILs	tumor infiltrating lymphocytes
TLR	toll-like receptors
TMB	tumor mutational burden
TNF-α	tumor necrosis factor α
TRAF6	tumor necrosis factor receptor-associated factor 6
T reg	regulatory T cells
VC	vulvar cancer
VHSIL	vulvar high-grade squamous intraepithelial neoplasia
VPD	vulvar Paget’s disease
VSCC	vulvar squamous cell carcinoma