Table 2.
Comparison of singleplex and multiplex testing of patient bone marrow (BM) and peripheral blood (PB) samples.
| Marker | BM (n = 24) | PB (n = 21) | ||
|---|---|---|---|---|
| MPX Positive BM Samples | Singpleplex Positive BM Samples | MPX Positive PB Samples | Singleplex Positive PB Samples | |
| PHOX2B | 24 | 24 | 20 | 19 |
| TH | 22 | 22 | 13 | 18 |
| CHRNA3 | 20 | 20 | 16 | 16 |
| GAP43 | 24 | 18 | ||
| DBH | 18 | 21 | ||
| Total ADRN | 24 * | 24 | 20 ** | 21 |
| PRRX1 | 9 | 9 | 0 | 0 |
| POSTN | 7 | 6 | 0 | 0 |
| Total MES | 11 *** | 10 | 0 | 0 |
* Sensitivity of 100% compared to the singleplex RT-qPCR in the BM cohort. ** Sensitivity of 95% compared to singleplex RT-qPCR in the PB cohort. *** Sensitivity of 80% compared to singleplex RT-qPCR in the BM cohort.